| Fri, Oct 2 | @ |   Dallas Stars | W 4–0 | 1-0-0 | TNT, truTV, HBO MAX, SN1 |
| Sat, Oct 3 | @ |   Colorado Avalanche | L 1–6 | 1-1-0 | STLNHL, BN+, ALT |
| Tue, Oct 6 | @ |   Chicago Blackhawks | L 2–4 | 1-2-0 | STLNHL, BN+, CHSN |
| Thu, Oct 8 | vs |   San Jose Sharks | L 2–3 (OT) | 1-2-1 | ESPN+, HULU, Disney+, SN+ |
| Sat, Oct 10 | vs |   Columbus Blue Jackets | W 5–3 | 2-2-1 | STLNHL, BN+, CBJNHL, CBJHN |
| Tue, Oct 13 | @ |   Ottawa Senators | W 7–2 | 3-2-1 | TSN5, RDSI, STLNHL, BN+ |
| Thu, Oct 15 | @ |   Minnesota Wild | 8:00 PM ET | | MINNHL, STLNHL, BN+, Wild+ |
| Sat, Oct 17 | @ |   Nashville Predators | 8:00 PM ET | | SCRIPPS, STLNHL, BN+ |
| Tue, Oct 20 | vs |   Winnipeg Jets | 8:00 PM ET | | STLNHL, BN+, TSN3 |
| Thu, Oct 22 | vs |   Vegas Golden Knights | 8:00 PM ET | | STLNHL, BN+, ABC32, SCRIPPS |
| Sat, Oct 24 | vs |   Carolina Hurricanes | 7:00 PM ET | | STLNHL, BN+, CARNHL, HHN |
| Tue, Oct 27 | vs |   Montréal Canadiens | 8:00 PM ET | | STLNHL, BN+, TSN2, RDS |
| Thu, Oct 29 | vs |   Boston Bruins | 8:00 PM ET | | STLNHL, BN+, NESN |
| Sat, Oct 31 | @ |   Detroit Red Wings | 1:00 PM ET | | STLNHL, BN+, DSN |
| Tue, Nov 3 | @ |   New York Rangers | 7:00 PM ET | | MSG, STLNHL, BN+ |
| Thu, Nov 5 | @ |   New Jersey Devils | 7:00 PM ET | | MSGSN, STLNHL, BN+, ABC32 |
| Sat, Nov 7 | @ | Nashville Predators | 1:00 PM ET | | SN+, SCRIPPS, STLNHL, BN+ |
| Tue, Nov 10 | vs | Detroit Red Wings | 8:00 PM ET | | TNT, truTV, HBO MAX, SN+ |
| Thu, Nov 12 | @ |   Utah Mammoth | 9:00 PM ET | | STLNHL, BN+, Mammoth+, Utah16 |
| Sat, Nov 14 | vs |   Florida Panthers | 7:00 PM ET | | STLNHL, BN+, SCRIPPS |
| Tue, Nov 17 | vs |   Anaheim Ducks | 8:00 PM ET | | STLNHL, BN+, Prime Video, KTTV |
| Thu, Nov 19 | @ |   Pittsburgh Penguins | 7:00 PM ET | | SN-PIT, STLNHL, BN+, ABC32 |
| Sat, Nov 21 | vs | New Jersey Devils | 7:00 PM ET | | MSGSN, STLNHL, BN+ |
| Sun, Nov 22 | vs |   Edmonton Oilers | 7:00 PM ET | | SN, STLNHL, BN+ |
| Wed, Nov 25 | @ |   New York Islanders | 7:00 PM ET | | MSGSN, STLNHL, BN+ |
| Fri, Nov 27 | vs | Dallas Stars | 2:00 PM ET | | SN+, STLNHL, BN+, Prime Video |
| Sat, Nov 28 | vs |   Washington Capitals | 7:00 PM ET | | STLNHL, BN+, MNMT2 |
| Wed, Dec 2 | vs | Pittsburgh Penguins | 8:00 PM ET | | SN-PIT, STLNHL, BN+ |
| Fri, Dec 4 | vs | Chicago Blackhawks | 8:00 PM ET | | STLNHL, BN+, CHSN |
| Sun, Dec 6 | vs | Nashville Predators | 5:00 PM ET | | SN360, SCRIPPS, STLNHL, BN+ |
| Tue, Dec 8 | vs | Colorado Avalanche | 8:00 PM ET | | ESPN+, HULU, Disney+ |
| Thu, Dec 10 | @ | Utah Mammoth | 9:00 PM ET | | STLNHL, BN+, Mammoth+, Utah16 |
| Sat, Dec 12 | @ | Dallas Stars | 8:00 PM ET | | STLNHL, BN+, Prime Video |
| Sun, Dec 13 | vs |   Tampa Bay Lightning | 8:00 PM ET | | SN+, STLNHL, BN+, The Spot |
| Tue, Dec 15 | vs | Winnipeg Jets | 8:00 PM ET | | STLNHL, BN+, TSN3 |
| Thu, Dec 17 | @ | Boston Bruins | 7:00 PM ET | | TVAS, STLNHL, BN+, ABC32, NESN |
| Sat, Dec 19 | @ | Washington Capitals | 7:00 PM ET | | STLNHL, BN+, MNMT |
| Mon, Dec 21 | @ | Florida Panthers | 7:00 PM ET | | TVAS, STLNHL, BN+, SCRIPPS |
| Tue, Dec 22 | @ | Tampa Bay Lightning | 7:00 PM ET | | TNT, truTV, HBO MAX, SN+ |
| Sun, Dec 27 | vs | New York Rangers | 5:00 PM ET | | SN+, MSG 2, STLNHL, BN+ |
| Tue, Dec 29 | @ | Colorado Avalanche | 9:00 PM ET | | STLNHL, BN+, ALT, KTVD |
| Thu, Dec 31 | @ | Vegas Golden Knights | 3:00 PM ET | | SN, STLNHL, BN+, ABC32, SCRIPPS |
| Sat, Jan 2 | @ | Minnesota Wild | 7:00 PM ET | | STLNHL, BN+, MINNHL, Wild+ |
| Sun, Jan 3 | vs |   Calgary Flames | 7:00 PM ET | | STLNHL, BN+, SNW |
| Tue, Jan 5 | @ | Carolina Hurricanes | 7:00 PM ET | | STLNHL, BN+, CARNHL, HHN |
| Fri, Jan 8 | vs | Ottawa Senators | 8:00 PM ET | | SN, RDS, STLNHL, BN+ |
| Wed, Jan 13 | @ |   Los Angeles Kings | 10:00 PM ET | | STLNHL, BN+, ABTV |
| Thu, Jan 14 | @ | Anaheim Ducks | 10:00 PM ET | | SN, STLNHL, BN+, Prime Video, KCOP-13 |
| Sat, Jan 16 | vs | Minnesota Wild | 7:00 PM ET | | STLNHL, BN+, MINNHL, Wild+, KSTC |
| Mon, Jan 18 | @ |   Toronto Maple Leafs | 7:30 PM ET | | SN+, STLNHL, BN+ |
| Thu, Jan 21 | @ | Montréal Canadiens | 7:00 PM ET | | STLNHL, BN+, ABC32, TSN2, RDS |
| Sat, Jan 23 | vs | Toronto Maple Leafs | 7:00 PM ET | | SNO, STLNHL, BN+ |
| Tue, Jan 26 | vs | Chicago Blackhawks | 8:00 PM ET | | ESPN+, HULU, Disney+, SN+ |
| Thu, Jan 28 | vs | Colorado Avalanche | 8:00 PM ET | | STLNHL, BN+, ABC32, ALT |
| Sat, Jan 30 | vs |   Vancouver Canucks | 3:30 PM ET | | SN, STLNHL, BN+ |
| Tue, Feb 9 | vs | Los Angeles Kings | 8:00 PM ET | | SN+, STLNHL, BN+, ABTV |
| Fri, Feb 12 | @ | Edmonton Oilers | 8:00 PM ET | | SN, STLNHL, BN+ |
| Sat, Feb 13 | @ |   Seattle Kraken | 10:00 PM ET | | Prime Video, KONG, STLNHL, BN+ |
| Mon, Feb 15 | vs |   Philadelphia Flyers | 8:00 PM ET | | NBCSP, STLNHL, BN+ |
| Wed, Feb 17 | @ | Chicago Blackhawks | 7:30 PM ET | | STLNHL, BN+, CHSN |
| Fri, Feb 19 | @ | Winnipeg Jets | 7:00 PM ET | | STLNHL, BN+, TSN3 |
| Sun, Feb 21 | vs | Utah Mammoth | 6:00 PM ET | | STLNHL, BN+, Mammoth+, Utah16 |
| Thu, Feb 25 | vs | Vancouver Canucks | 8:00 PM ET | | STLNHL, BN+, ABC32, SNP |
| Sat, Feb 27 | vs | Minnesota Wild | 4:00 PM ET | | SN+, STLNHL, BN+, MINNHL, Wild+ |
| Sun, Feb 28 | vs | Dallas Stars | 9:00 PM ET | | ESPN, SN |
| Thu, Mar 4 | @ |   Buffalo Sabres | 7:00 PM ET | | STLNHL, BN+, MSG-B |
| Sun, Mar 7 | @ | Philadelphia Flyers | 3:30 PM ET | | TNT, truTV, HBO MAX, SN+ |
| Tue, Mar 9 | vs | Nashville Predators | 8:00 PM ET | | SCRIPPS, STLNHL, BN+ |
| Thu, Mar 11 | vs | San Jose Sharks | 8:00 PM ET | | NBCSCA, STLNHL, BN+, ABC32 |
| Sat, Mar 13 | vs | Anaheim Ducks | 6:30 PM ET | | STLNHL, BN+, Prime Video, KCOP-13 |
| Mon, Mar 15 | @ | Seattle Kraken | 9:40 PM ET | | Prime Video, KONG, STLNHL, BN+ |
| Thu, Mar 18 | @ | Edmonton Oilers | 9:00 PM ET | | TVAS, STLNHL, BN+, SNW |
| Sat, Mar 20 | @ | Vancouver Canucks | 10:00 PM ET | | SNP, TVAS, STLNHL, BN+ |
| Sun, Mar 21 | @ | Calgary Flames | 8:00 PM ET | | STLNHL, BN+, SNW |
| Tue, Mar 23 | @ | Winnipeg Jets | 8:00 PM ET | | STLNHL, BN+, TSN3 |
| Thu, Mar 25 | vs | New York Islanders | 8:00 PM ET | | SN+, MSGSN2, STLNHL, BN+, ABC32 |
| Sat, Mar 27 | @ | Columbus Blue Jackets | 7:00 PM ET | | STLNHL, BN+, CBJNHL, CBJHN |
| Sun, Mar 28 | vs | Buffalo Sabres | 8:30 PM ET | | ESPN, SN |
| Thu, Apr 1 | vs | Calgary Flames | 8:00 PM ET | | SNW, STLNHL, BN+ |
| Sat, Apr 3 | @ | Los Angeles Kings | 10:30 PM ET | | STLNHL, BN+, ABTV |
| Sun, Apr 4 | @ | San Jose Sharks | 9:30 PM ET | | ESPN, SN360 |
| Tue, Apr 6 | @ | Vegas Golden Knights | 10:30 PM ET | | ESPN, SN360 |
| Thu, Apr 8 | vs | Seattle Kraken | 8:00 PM ET | | Prime Video, KING, KONG, STLNHL, BN+ |
| Sat, Apr 10 | vs | Utah Mammoth | 7:00 PM ET | | STLNHL, BN+, Mammoth+, Utah16 |
